Motor Learning in Duchenne Muscular Dystrophy, a Literature Review

Authors

  • Silvia Regina Pinheiro Malheiros
  • Denise Cardoso Ribeiro
  • Mayra Priscila Bolcolo Alvarez
  • Bruna Leal de Freitas
  • Camila Miliani Capelini
  • Thais Massetti
  • Talita Dias da Silva
  • Luiz Carlos de Abreu Faculdade de Medicina do ABC. Departamento de Saúde da Coletividade. Disciplina de Metodologia Científica.
  • Rubens Wajnsztejn
  • Carlos Bandeira de Mello Monteiro

DOI:

https://doi.org/10.3823/1816

Keywords:

“Duchenne muscular dystrophy”, “motor learning”, “motor abilities”.

Abstract

OBJECTIVE: To present and discuss the outcomes in the literature regarding the process of motor learning and/or motor ability in people with Duchenne muscular dystrophy (DMD).

METHOD: A timeless search was performed in the electronic databases PubMed and BVS (Virtual Health Library), with the keywords “Duchenne muscular dystrophy†(Duchenne Muscular Dystrophy), “motor learning†(learning engine), “motor skills†(ability motor). We used the Boolean AND / OR, and / or to give more specific research and sensitivity to the survey, and papers were only accepted in Portuguese and English. The studies were reviewed independently by two researchers, and after reading the titles and abstracts, they identified the works that were included for analysis and scoring.

RESULTS: The search yielded 18 articles and four studies met all inclusion criteria. The results show that DMD maintains motor learning patterns, even with the progressive dysfunction. They also focus on lower performance compared to individuals with normal development. However, there are differences in the impact and magnitude of the influence of factors such as cognitive ability, deterioration of the perceptual motor process and kinetic impairment in the motor learning of people with DMD.

CONCLUSION: The process of motor learning in people with DMD remains, even with the progressive nature of the disease, and it is essential to further clarify how this process takes place, as well as the variables behave.

References

K.M. Flanigan, Duchenne and Becker muscular dystrophies, Neurol Clin, 32 (2014) 671-688, viii.

H. Foster, L. Popplewell, G. Dickson, Genetic therapeutic approaches for Duchenne muscular dystrophy, Hum Gene Ther, 23 (2012) 676-687.

A. Nakafuji, K. Tsuji, Learning and transfer in two perceptual-motor skills in Duchenne muscular dystrophy, Percept Mot Skills, 93 (2001) 339-352.

M. Kohler, C.F. Clarenbach, C. Bahler, T. Brack, E.W. Russi, K.E. Bloch, Disability and survival in Duchenne muscular dystrophy, J Neurol Neurosurg Psychiatry, 80 (2009) 320-325.

N.M. Santos, M. Rezende, A. Terni, M.C.B. Hayashi, F.M. Fávero, A.A.J. Quadros, L. Reis, M. Adissi, A.L. Langer, S.V. Fontes, Perfil clínico e funcional dos pacientes com distrofia muscular de Duchenne assistidos na Associação Brasileira de Distrofia Muscular (ABDIM), Rev Neurociênc, 14 (2006) 15-22.

F. Cincotti, D. Mattia, F. Aloise, S. Bufalari, G. Schalk, G. Oriolo, A. Cherubini, M.G. Marciani, F. Babiloni, Non-invasive brain-computer interface system: towards its application as assistive technology, Brain Res Bull, 75 (2008) 796-803.

M. Jansen, I.J. de Groot, N. van Alfen, A. Geurts, Physical training in boys with Duchenne Muscular Dystrophy: the protocol of the No Use is Disuse study, BMC Pediatr, 10 (2010) 55.

L.R. Peddareddygari, B.H. Pillai, D. Nochlin, L.R. Sharer, R.P. Grewal, Phenotype-genotype analysis of dystrophinopathy caused by duplication mutation in Dystrophin gene in an African patient, Afr Health Sci, 11 (2011) 607-609.

L. Bello, P. Melacini, R. Pezzani, A. D'Amico, L. Piva, E. Leonardi, A. Torella, G. Soraru, A. Palmieri, G. Smaniotto, B.F. Gavassini, A. Vianello, V. Nigro, E. Bertini, C. Angelini, S.C. Tosatto, E. Pegoraro, Cardiomyopathy in patients with POMT1-related congenital and limb-girdle muscular dystrophy, Eur J Hum Genet, 20 (2012) 1234-1239.

M. Jover, C. Schmitz, E. Bosdure, B. Chabrol, C. Assaiante, Anticipatory postural adjustments in a bimanual load-lifting task in children with Duchenne muscular dystrophy, Neurosci Lett, 403 (2006) 271-275.

K. Bushby, E. Connor, Clinical outcome measures for trials in Duchenne muscular dystrophy: report from International Working Group meetings, Clin Investig (Lond), 1 (2011) 1217-1235.

N. Juretic, G. Jorquera, P. Caviedes, E. Jaimovich, N. Riveros, Electrical stimulation induces calcium-dependent up-regulation of neuregulin-1beta in dystrophic skeletal muscle cell lines, Cell Physiol Biochem, 29 (2012) 919-930.

V. Malik, L.R. Rodino-Klapac, J.R. Mendell, Emerging drugs for Duchenne muscular dystrophy, Expert Opin Emerg Drugs, 17 (2012) 261-277.

V. Raman, D. Yacob, J.D. Tobias, Dexmedetomidine-ketamine sedation during upper gastrointestinal endoscopy and biopsy in a patient with Duchenne muscular dystrophy and egg allergy, Int J Crit Illn Inj Sci, 2 (2012) 40-43.

L. Merlini, M. Gennari, E. Malaspina, I. Cecconi, A. Armaroli, S. Gnudi, B. Talim, A. Ferlini, A. Cicognani, E. Franzoni, Early corticosteroid treatment in 4 Duchenne muscular dystrophy patients: 14-year follow-up, Muscle Nerve, 45 (2012) 796-802.

J. Visser, Developmental coordination disorder: a review of research on subtypes and comorbidities, Hum Mov Sci, 22 (2003) 479-493.

Y. Hashimoto, J. Ushiba, A. Kimura, M. Liu, Y. Tomita, Change in brain activity through virtual reality-based brain-machine communication in a chronic tetraplegic subject with muscular dystrophy, BMC Neurosci, 11 (2010) 117.

R. Leeb, F. Lee, C. Keinrath, R. Scherer, H. Bischof, G. Pfurtscheller, Brain-computer communication: motivation, aim, and impact of exploring a virtual apartment, IEEE Trans Neural Syst Rehabil Eng, 15 (2007) 473-482.

T. Kitago, J.W. Krakauer, Motor learning principles for neurorehabilitation, Handb Clin Neurol, 110 (2013) 93-103.

C.B.d.M. Monteiro, C.M. Jakabi, G.C.d.S. Palma, C. Torriani-Pasin, M. Junior, C. de Miranda, Aprendizagem motora em crianças com paralisia cerebral, Revista brasileira de crescimento e desenvolvimento humano, 20 (2010) 250-262.

D.C.G.L. Fernani, M.T.A. Prado, R.F. Fell, N.L.d. Reis, T.C. Bofi, E.B. Ribeiro, M.d.T. Blake, C.B.d.M. Monteiro, Motor intervention on children with school learning dificulties, Revista brasileira de crescimento e desenvolvimento humano, 23 (2013) 209-214.

C. Martinez Carrasco, M. Cols Roig, A. Salcedo Posadas, O. Sardon Prado, O. Asensio de la Cruz, A. Torrent Vernetta, [Respiratory treatments in neuromuscular disease], An Pediatr (Barc), 81 (2014) 259.e251-259.

L. Snider, A. Majnemer, V. Darsaklis, Virtual reality as a therapeutic modality for children with cerebral palsy, Dev Neurorehabil, 13 (2010) 120-128.

T. Massetti, T.D. da Silva, D.C. Ribeiro, S.R.P. Malheiros, A.H.N. Re, F.M. Favero, C.B. de Mello Monteiro, Motor learning through virtual reality in cerebral palsy–a literature review, MedicalExpress, 1 (2014) 302-306.

R.F. Sampaio, M.C. Mancini, Estudos de revisão sistemática: um guia para síntese criteriosa da evidência científica, Braz. J. Phys. Ther.(Impr.), 11 (2007) 83-89.

S.L. Parreira, M.B. Resende, M. Della Corte Peduto, S.K. Marie, M.S. Carvalho, U.C. Reed, Quantification of muscle strength and motor ability in patients with Duchenne muscular dystrophy on steroid therapy, Arq Neuropsiquiatr, 65 (2007) 245-250.

S.L. Parreira, M.B. Resende, E. Zanoteli, M.S. Carvalho, S.K. Marie, U.C. Reed, Comparison of motor strength and function in patients with Duchenne muscular dystrophy with or without steroid therapy, Arq Neuropsiquiatr, 68 (2010) 683-688.

D. Beaton, C. Bombardier, F. Guillemin, M.B. Ferraz, Recommendations for the cross-cultural adaptation of the DASH & QuickDASH outcome measures, Institute for Work & Health, 1 (2007) 1-45.

F.R. van der Weel, A.L. van der Meer, D.N. Lee, Effect of task on movement control in cerebral palsy: implications for assessment and therapy, Dev Med Child Neurol, 33 (1991) 419-426.

S.E. Cyrulnik, R.J. Fee, A. Batchelder, J. Kiefel, E. Goldstein, V.J. Hinton, Cognitive and adaptive deficits in young children with Duchenne muscular dystrophy (DMD), J Int Neuropsychol Soc, 14 (2008) 853-861.

K. Uchikawa, M. Liu, K. Hanayama, T. Tsuji, T. Fujiwara, N. Chino, Functional status and muscle strength in people with Duchenne muscular dystrophy living in the community, J Rehabil Med, 36 (2004) 124-129.

Downloads

Published

2015-09-19

Issue

Section

Neuroscience

Most read articles by the same author(s)

<< < 1 2 3 4 > >>