Herbal anti-edematous agents for certain cases of facial cellulitis of odontogenic origin. Clinical recommendation.

Authors

  • Najla S. Dar-Odeh Professor, Faculty of dentistry, University of Jordan, Amman, Jordan
  • Shaden Abu-Hammad
  • Osama Abu-Hammad

DOI:

https://doi.org/10.3823/825

Keywords:

Aescin, Antibiotics, Bromelain, Cellulitis, Dental, Edema, Herbal, Lips

Abstract

Literature from different parts of the world reported that antibiotic abuse is evident in dental practice. One aspect of this abuse is prescribing antibiotics for non-indicated orofacial infections. The use of some herbal anti-edematous agents has been recommended for reducing post-operative swelling/edema in certain oral and maxillofacial surgical procedures. In this review we describe the possible benefits of using these agents for certain cases of facial cellulitis in order to reduce the number of antibiotic prescriptions for this particular clinical situation.

References

Dar-Odeh, Najla S, Al-Beyari M, Abu-Hammad OA. The role of

antifungal drugs in the management of stomatitis. Int Arab J

Antimicrob Agents 2012;2:1-5. doi:10.3823/705.

Dar-Odeh NS, Al-Abdalla M, Al-Shayyab MH, Obeidat H,

Obeidat L, Kar MA, et al. Prescribing Antibiotics for pediatric

dental patients in Jordan; knowledge and attitudes of dentists.

Int Arab J Antimicrob Agents 2013;3:4. doi:10.3823/736.

Tomczyk S, Whitten T, Holzbauer SM LR. Combating antibiotic

resistance: a survey on the antibiotic-prescribing habits of

dentists. Gen Dent 2018;66:61–8.

Bird L, Landes D, Robson T, Sturrock A LJ. Higher antibiotic

prescribing propensity of dentists in deprived areas and those

with greater access to care in the North East and Cumbria, UK.

Br Dent J 2018;225:517-24.

Greenstein, Gary, Greenstein B. Clinical Management of Acute

Orofacial Infections. Compend Contin Educ Dent 2015;36:96-

Dar-Odeh N, Fadel HT, Abu-Hammad S, Abdeljawad R, Abu-

Hammad OA. Antibiotic prescribing for Oro-facial infections

in the paediatric outpatient: A review. Antibiotics 2018;7.

doi:10.3390/antibiotics7020038.

ipahi Calis A, Ozveri Koyuncu B, Ozturk K, Mert A BC. General

approach to the treatment of odontogenic abscesses and cost

analysis. J Istanb Univ Fac Dent 2015;49:17-22.

Majid OW, Al-Mashhadani BA. Perioperative bromelain reduces

pain and swelling and improves quality of life measures after

mandibular third molar surgery: A randomized, double-blind,

placebo-controlled clinical trial. J Oral Maxillofac Surg 2014.

doi :10.1016/ j . j oms. 2013.12. 035.

Singh T, More V, Fatima U, Karpe T, Aleem MA, Prameela J.

Effect of proteolytic enzyme bromelain on pain and swelling

after removal of third molars. J Int Soc Prev Community Dent

doi:10.4103/ 2231- 0762.197192.

Ghensi P, Cucchi A, Creminelli L, Tomasi C, Zavan B, Maiorana

C. Effect of Oral Administration of Bromelain on Postoperative

Discomfort after Third Molar Surgery. J Craniofac Surg 2017.

doi:10.1097/SCS.0000000000003154.

Domanski D, Zegrocka-Stendel O, Perzanowska A, Dutkiewicz

M, Kowalewska M, Grabowska I, et al. Molecular mechanism

for cellular response to β-escin and its therapeutic implications.

PLoS One 2016. doi:10.1371/journal.pone.0164365.

Tiffany N, Boon H, Ulbricht C, Basch E, Bent S, Barrette EP, et

al. Horse chestnut:a multidisciplinary clinical review. J Herb

Pharmacother 2002.

Frick RW. Three treatments for chronic venous insufficiency:

Escin, hydroxyethylrutoside, and Daflon. Angiology 2000.

doi:10.1177/000331970005100303.

Gupta SC, Tyagi AK, Deshmukh-Taskar P, Hinojosa M, Prasad

S, Aggarwal BB. Downregulation of tumor necrosis factor

and other proinflammatory biomarkers by polyphenols. Arch

Biochem Biophys 2014. doi:10.1016/j.abb.2014.06.006.

Ottillinger B, Greeske K. Rational therapy of chronic venous

insufficiency - Chances and limits of the therapeutic use of

horse-chestnut seeds extract. BMC Cardiovasc Disord 2001.

doi:10.1186/1471-2261-1-5.

Wilkinson JA, Brown AMG. Horse chestnut - Aesculus

hippocastanum: Potential applications in cosmetic skincare

products.

Int

J Cosmet

Sci

doi:10.1046/j.14672494.1999.234192.x.

Dudek-Makuch M, Studzińska-Sroka E. Horse chestnut - efficacy

and safety in chronic venous insufficiency: an overview. Rev Bras

Farmacogn 2015. doi:10.1016/j.bjp.2015.05.009.

Bayer G. Martindale: The Complete Drug Reference. 38th ed.

Aust Prescr 2015. doi:10.18773/austprescr.2015.023.

Taussig SJ. The mechanism of the physiological action

of bromelain. Med Hypotheses 1980. doi:10.1016/03069877(80)90038-9.

Orsini RA. Bromelain. Plast Reconstr Surg 2006. doi:10.1097/01.

prs.0000242503.50548.ee.

Ordesi P, Pisoni L, Nannei P, Macchi M, Borloni R, Siervo S.

Therapeutic efficacy of bromelain in impacted third molar

surgery: A randomized controlled clinical study. Quintessence

Int (Berl) 2014. doi:10.3290/j.qi.a32237.

Bormann KH, Weber K, Kloppenburg H, Koch A, Meiser P,

Gellrich NC. Perioperative Bromelain Therapy after Wisdom

Teeth Extraction - A Randomized, Placebo-Controlled, DoubleBlinded,

Three-Armed,

Cross-Over

Dose-Finding

Study.

Phyther

Res

doi:10.1002/ptr.5707.

Zatuchni GI, Colombi DJ. Bromelains therapy for the prevention

of episiotomy pain. Obstet Gynecol 1967.

de R, de Sousa Lima FCM, do BC. Is bromelain an effective

drug for the control of pain and inflammation associated

with impacted third molar surgery? Systematic review and

meta-analysis. Int J Oral Maxillofac Surg 2018. doi:10.1016/j.

ijom.2018.07.028.

Maurer HR. Bromelain: Biochemistry, pharmacology and medical

use. Cell Mol Life Sci 2001. doi:10.1007/PL00000936.

Reddy KK, Grossman L, Rogers GS. Common complementary

and alternative therapies with potential use in dermatologic

surgery: Risks and benefits. J Am Acad Dermatol 2013.

doi:10.1016/j.jaad.2011.06.030.

Morse DR. Oral Pathways of Infection. Int Endod J 1972.

doi :10.1111/ j .1365-2591.1972.t b00064. x.

Obayashi N, Ariji Y, Goto M, Izumi M, Naitoh M, Kurita K, et

al. Spread of odontogenic infection originating in the maxillary

teeth: Computerized tomographic assessment. Oral Surgery,

Oral Med Oral Pathol Oral Radiol Endodontology 2004.

doi:10.1016/j.tripleo.2004.05.014.

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2018-12-11

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