Pregnancy Complications and Perinatal Outcomes of Women with Hemoglobinopathies


  • Eliny Aparecida Vargas Machado Salazar
  • Maria Lúcia Ivo
  • Sandra Luzinete Félix de Freitas
  • Maria Stella Figueiredo
  • Maria Auxiliadora de Souza Gerk
  • Cristina Brandt Nunes
  • Berenice Assumpção Kikuchi
  • Elenir Rose Jardim Cury Pontes
  • Ernesto Antonio Figueiró-Filho
  • Thais Priscila Biassi
  • Isabelle Campos de Azevedo Federal University of Rio Grande do Norte
  • Rita de Cássia Lira da Silva
  • Marcos Antonio Ferreira Júnior



Objective: To estimate the prevalence of gestational complications and perinatal outcomes in women with and without hemoglobinopathies. Method: This is a cross-sectional study with a quantitative approach, performed from 110 medical records of pregnant women who underwent prenatal, childbirth, postpartum and perinatal care in a gynecology and obstetrics service of the University Hospital at the Federal University of Mato Grosso do Sul, Brazil, between 2010 and 2011. Results: Gestational complications in women with and without hemoglobinopathies in the variables: obstetric (preterm labor, pre-eclampsia, ruptured membranes for more than six hours (17.06 times; 12.19 times; 4.27 times respectively); clinical: urinary tract infection, heart failure, severe anemia (2.97 times; 12.6 times;  9.75 times, respectively), and perinatal: cesarean delivery, neonatal infection; the newborn in the neonatal intensive care unit; fetal death, stillbirth (1.57 times; 39.00 times; 12.19 times; 12.9 times; 9.75 times; respectively) were higher in the presence of hemoglobinopathies. Conclusion: The pregnancy outcomes of women with hemoglobinopathies, perinatal and their newborns showed a higher prevalence of complications than women without this change.

Keywords: Hemoglobinopathies; Pregnancy Complications, Hematologic; Perinatal Care.

Author Biography

Isabelle Campos de Azevedo, Federal University of Rio Grande do Norte

Nurse. Master's Student in Post-Graduate Program in Nursing of the Federal University of Rio Grande do Norte. Natal/RN, Brazil.







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