Major infections in hospitalized patients with stroke: a prospective study


  • Flavia Mendes de Sá Msc, Nurse, Post-Graduate Program, Nursing Department, Faculty of Medicine of Botucatu, Universidade Estadual Paulista "Julio de Mesquita Filho", Botucatu, SP.
  • Cassiana Mendes Bertoncello Fontes PhD, Assistant Professor, Nursing Department, Faculty of Medicine of Botucatu, Universidade Estadual Paulista "Julio de Mesquita Filho", Botucatu, SP.
  • Alessandro Lia Mondelli M.D., Assistant Professor, Medical Clinic Department, Faculty of Medicine of Botucatu, Universidade Estadual Paulista "Julio de Mesquita Filho", Botucatu, SP.



stroke; infection; risk, stroke, infection, risk.


Objective: to describe the occurrence of infection in patients with stroke. Materials and Methods: a cohort prospective study of 143 patients admitted to a stroke unit from december / 2014 to june / 2015. Results: the mean age was 67.8 years with history of hypertension and ischemic stroke; the main infections were related to the respiratory (8.4%) and urinary tract (7.7%); the invasive devices used, were: peripheral venous access (95.1%) and  nasoenteral tube (31.25%); the prevalent microorganisms were escherichia coli and MRSA. Protections to occurrence of infection were related to:  non-alcoholic patients and non- HIV infection carriers; non-use of urinary catheter and endotracheal intubation (p> 0.05); presence of hemorrhagic stroke predisposed to occurrence of urinary tract infection (p> 0.05). Conclusion:  prognosis of the patient depends on the type of stroke and occurrence of infections related to health care.



MAGILL, S. S.; EDWARDS, J. R.; BAMBERG, W.; BELDAYS, Z. G.; DUMYATI, G.; KAINER, M. A.; FRIDKIN, et al. Multistate point-prevalence survey of health care– associated infections. New England Journal of Medicine, v. 370, n. 13, p. 1198- 1208, 2014

WANG, P.L.; ZHAO, X.Q.; YANG, Z.H.; WANG, A.X.; WANG, C.X.; LIU, L.P.; et al. Effect of in-hospital medical complications on case fatality postacute ischemic stroke: data from the China National Stroke Registry. Chin Med J. v. 125, n. 14, p. 2449-54, 2012. Disponível em:

POPOVIC, N.; STEFANOVIC-BIDUMKIC, M.; MITROVIC, N.; UROSEVIC, A.; MILOSEVIC, B.; et al. The Frequency of poststroke Infections and Their Impact in Early Stroke Outcome. J Stroke Cerebrovasc Dis. v. 22, n. 4, p. 424-29, 2013: Disponível em:

PINA, E.; FERREIRA, E.; MARQUES, A.; MATOS, B. Infecções associadas aos cuidados em saúde e segurança do doente. Rev Port Saúde Pública, v. 10, p. 27- 39, set. 2010

KLEHMET, J.; HARMS, H; RICHTER, M.; PRASS, K.; VOLK, H. D.; DIRNAGL, U.; MEISEL, A.; MEISEL, C. Stroke-induced immunodepression and post-stroke infections: lessons from the preventive antibacterial therapy in stroke trial. Neuroscience, v. 158, n. 3, p. 1184-1193, 2009

GO, A. S.; MOZAFFARIAN, D., ROGER, V. L. et al. Heart disease and stroke statistics-2014 update: a report from the American Heart Association. Circulation, v. 127, n. 1, p. e6–e245, 2014.

RADANOVIC, M. Características do atendimento de pacientes com acidente vascular cerebral em hospital secundário. Arq. Neuro-Psiquiatr., v. 58, n. 1, p. 99- 106, 2000

JOHNSEN, S.P.; SVENDSEN, M.L.; INGEMAN, A. Infection in Patients with Acute Stroke. The Open Infectious Diseases Journal. v. 6, n. 1, p. 40-45, 2012

WASTENDORP, W.F.; NEDEERKORN, J.P.; VERMEIJ, J.D.; DIJKGRAAF, M.G.; BEEK, D. Post-stroke infection: A systematic review and meta-analysis. BMC Neurology. v. 11, n. 110, p. 1-7, 2011. Disponível em:

GOMES, A.C.; CARVALHO, P.O.; LIMA, E.T.A.; GOMES, E.T.; VALENCA, M.P.; CAVALCANTI, A.T.A. Carcaterização da infecções relacionadas à assistência à saúde em unidade de terapia intensiva. Rev enferm UFPE online. v. 8, n. 6, p. 1577-85, 2014. Disponível em: revistaenfermagem/index.php/revista/article/view/5618/pdf_5252

CARNESOLTAS, L.S.; VALDES, M.A.S.; LAZO, O.R. Factores de riesgo y mortalidad por neumonía intrahospitalaria em la Unidad de Terapia Intensiva de Ictus. Medwave. v. 13, n. 2, p. 1-9, 2013. Disponível em: ave.20 13.02.5637.pdf

. INGEMAN, A.; ANDERSEN, G.; HEIDI, H.; SVENDSEN, M.I.; JOHNSEN, S.P. In- Hospital Medical Complications, Length of Stay, and Mortality Among Stroke Unit Patients. Stroke Journal of the American Heart Association. v. 42, n. 11, p. 3214- 3218, 2011

YU K.W.; LIN C.L.; HUNG C.C.; et al. Effects of electroacupuncture on recent stroke inpatients with incomplete bladder emptying: a preliminary study. Clinical Interventions in Aging. 2012;7:469-474. doi:10.2147/CIA.S37531. Disponível em:

LIAO, C.C.; SHIH, C.C.; YEH, C.C.; CHANG, Y.C.; HU, C.J.; LIN, J.G, et al. Impact of diabetes on stroke risk and outcomes: two nationwide retrospective cohort studies. MD Journal. v. 94, n. 52, p. 1-8, 2015

JI, R.; SHEN, H.; PAN, Y.; DU, W.; WANG, P.; LIU, G.; et al. Risk Score to Predict Hospital-Acquired Pneumonia after Spontaneous Intracerebral Hemorrhage. Stroke Journal of the American Heart Association. V. 45, n. 9, p. 2620-2628, 2014

PANDIAN, J.D.; ARSHPREET, K.; RASHMI, J.; PADMAVATI, N.S.; PAMIDIMUKKALA, V.; MADAKASIRA, V.P.; et al. Complications in Acute Stroke in India (CAST-I): A Multicenter Study. Journal of Stroke and Cerebrovascular Diseases. v. 21, n. 8, p. 695-708, 2012






Infectious Diseases