Incidence Profile of Leukemias, Lymphomas, Central Nervous System Tumors and Soft-Tissue Sarcomas in Children and Adolescents in a Brazilian City

Authors

  • Jane Kelly Oliveira Friestino School of Medical Sciences, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil.
  • Priscila Maria Stolses Bergamo Francisco School of Medical Sciences, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil.
  • Djalma de Carvalho Moreira Filho School of Medical Sciences, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil.

DOI:

https://doi.org/10.3823/2023

Keywords:

Child health, Adolescent health, Epidemiology, Neoplasms

Abstract

Objectives: To identify the profile of incidence of Leukemias, myeloproliferative diseases, and myelodysplastic diseases; Lymphomas and reticuloendothelial neoplasms; CNS and miscellaneous intracranial and intraspinal neoplasms and Soft tissue and other extraosseous sarcomas, in children and adolescents (aged ≤ 19) living in Campinas, São Paulo, Brazil.

Methods: This is an epidemiological study with data from medical records between 1996 and 2005, using the form of Population-based Cancer Registry of Campinas-SP, Brazil. Differences were identified among the groups and the spatial cluster analysis was conducted.

Results: The Leukemia cases were more representative (50%) than the others, followed by Lymphomas (22%), CNS (21%) and Soft Tissue (7%). In terms of sociodemographic variables, gender (p=0.03) and age (p<0.01) were significantly associated with cancer in the study groups. According to the spatial distribution of the cases, the Health Districts had a non-homogeneous distribution.

Conclusions: The distribution and characteristics of the diagnoses of the study groups were similar to the results of other studies on the subject. The incidence profile can help increase awareness of the occurrences and improve the healthcare planning.

 

Author Biographies

Jane Kelly Oliveira Friestino, School of Medical Sciences, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil.

Department of Collective Health, PhD candidate.

Priscila Maria Stolses Bergamo Francisco, School of Medical Sciences, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil.

Department of Collective Health. Professor.

Djalma de Carvalho Moreira Filho, School of Medical Sciences, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil.

Department of Collective Health. Professor.

References

Steliarova-Foucher E, Stiller C, Kaatsch P, Berrino F, Coebergh JW, Lacour B, et al. Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): an epidemiological study. Lancet. 2004;364(9451):2097-105.

Ward E, De Santis C, Robbins A, Kohler B, Jemal A. Childhood and adolescent cancer statistics, 2014. CA: A Cancer Journal for Clinicians. 2014;64(2):83-103.

Kaatsch P. Epidemiology of childhood cancer. Cancer treatment reviews. 2010;36(4):277-85.

Bailony MR, Hararah MK, Salhab AR, Ghannam I, Abdeen Z, Ghannam J. Cancer registration and healthcare access in West Bank, Palestine: a GIS analysis of childhood cancer, 1998-2007. International journal of cancer. 2011;129(5):1180-9.

INCA, Instituto Nacional do Câncer. Câncer na criança e no adolescente no Brasil: dados dos Registros de Base Populacional e de Mortalidade. Rio de Janeiro: INCA; 2008.

de Camargo B, de Oliveira Santos M, Rebelo MS, de Souza Reis R, Ferman S, Noronha CP, et al. Cancer incidence among children and adolescents in Brazil: first report of 14 population-based cancer registries. International jornal of cancer. 2010;126(3):715-20.

Reis RS, Santos, M.O., Thuler, L.C.S. Incidência de tumores pediátricos no Brasil. Revista Brasileira de Cancerologia. 2007;53(1):10.

Freire AM, Braga HA, Braga AA, Rolim Neto ML. Hope and Pediatric Cancer. International Archives of Medicine. 2015; 8(61):1-6.

Diniz AB RC, Brito NP, Conceição LS, Moreira LM. Perfil epidemiológico do câncer infantil em população atendida por uma unidade de oncologia pediátrica em Salvador-Bahia. Rev Ciênc Méd Biol 2005;4:131-9.

Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P. International Classification of Childhood Cancer, third edition. Cancer. 2005;103(7):1457-67.

Hung GY, Horng JL, Yen HJ, Lee CY, Lee YS. Geographic Variation in Cancer Incidence among Children and Adolescents in Taiwan (1995-2009). PLoS One. 2015;10(7):e0133051.

Stiller CA, Parkin DM. Geographic and ethnic variations in the incidence of childhood cancer. British medical bulletin. 1996;52(4):682-703.

Fritz APC, Jack A, Shanmugarathan S, Sobin L, Parkin DM, Whelan S. International Classification of Diseases for Oncology - ICD-O-3. World Health Organization ed. 3rd, editor. Geneva 2000.

INCA, Instituto Nacional do Câncer. Atlas da Mortalidade por Câncer no Brasil 1979-1999. Rio de Janeiro: INCA; 2002.

IBGE, Instituto Brasileiro de Geografia e Estatística. Cidades @ Campinas – SP; [Internet]. 2000 [updated 2015 Nov 01; cited 2016 May 05]. Available from: http://cidades.ibge.gov.br/xtras/perfil.php?lang=&codmun=350950&search=sao-paulo|campinas.

Laurenti R JM, Lebrão ML, Gotlieb SLD. Estatísticas de Saúde. 3. ed. São Paulo: E.P.U.; 2005.

Bailey TC. Interactive Spatial Data Analysis Malaysia: Longman Scientific &Technical 1995.

Martines WRV, Machado AL, Colvero LA. A cartografia como inovação metodológica na pesquisa em saúde. Rev Tempus Actas Saúde Col. 2013; 7(2): 203-211.

Gatta G, Botta L, Rossi S, Aareleid T, Bielska-Lasota M, Clavel J, et al. Childhood cancer survival in Europe 1999–2007: results of EUROCARE-5—a population-based study. The Lancet Oncology. 2014;15(1):35-47.20. Araújo OL, Trindade KM, Trompieri NM, Fontenele JB, Felix FH. Analysis of survival and prognostic factors of pediatric patients with brain tumor. Jornal de pediatria. 2011;87(5):425-32.

Leite EP, Muniz MTC, Azevedo ACAC, Souto FR, Maia ACL, Godim CMF et al. Fatores prognósticos em crianças e adolescentes com Leucemia Linfóide Aguda. Rev Bras Saude Mater Infant 2007;7(4):413-21.

Pedrosa MF, Pedrosa F, Lins MM, Pontes Neto NT, Falbo GH. Non-Hodgkin's lymphoma in childhood: clinical and epidemiological characteristics and survival analysis at a single center in Northeast Brazil. Jornal de pediatria. 2007;83(6):547-54.

Braga PE, Latorre MRDO, Curado MP. Câncer na infância: análise comparativa da incidência, mortalidade e sobrevida em Goiânia (Brasil) e outros países. Cad Saúde Pública. 2002;18:33-44.

Linabery AM, Ross JA. Childhood and adolescent cancer survival in the US by race and ethnicity for the diagnostic period 1975-1999. Cancer. 2008;113(9):2575-96.

Howlader N NA, Krapcho M, Garshell J, Neyman N, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Cho H, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds).. SEER Cancer Statistics Review, 1975-2010. Bethesda: National Cancer Institute, 2013.

Carreira H, Antunes L, Castro C, Lunet N, Bento MJ. Cancer incidence and survival (1997-2006) among adolescents and young adults in the north of Portugal. Pediatric hematology and oncology. 2012;29(7):663-76.

Krieger N, Chen JT, Waterman PD, Soobader MJ, Subramanian SV, Carson R. Geocoding and monitoring of US socioeconomic inequalities in mortality and cancer incidence: does the choice of area-based measure and geographic level matter?: the Public Health Disparities Geocoding Project. American jornal of epidemiology. 2002;156(5):471-82.

Sabroza PC. Estudos epidemiológicos na perspectiva do aumento da vulnerabilidade dos sistemas sócio-ambientais brasileiros. Epidemiol. Serv. Saúde. 2007;16(4):229-232.

Rodrigues KE, Camargo Bd. Diagnóstico precoce do câncer infantil: responsabilidade de todos. Revista da Associação Médica Brasileira. 2003; 49:29-34.

Dang-Tan T, Franco EL. Diagnosis delays in childhood cancer: a review. Cancer. 2007;110(4):703-13.

Parkin DM, Kramárová E, Draper GJ, Masuyer E. International incidence of childhood cancer. 144o ed. lyon: IARC; 1998.

Reis SR, Santos MO, de Camargo B, Oliveira JF, Thuler LC, Pombo-de-Oliveira MS. Early childhood leukemia incidence trends in Brazil. Pediatric Hematology and Oncology. 2016; 33(2):83-93.

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Published

2016-07-30

Issue

Vol. 9 (2016)

Section

Oncology

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