Studies on Survival of Corneal Tissue Transplantation in Patients with Keratoconus

  • Giovanna Karinny Pereira Cruz Federal University of Rio Grande do Norte
  • Diana Paula de Souza Rego Pinto Carvalho Federal University of Rio Grande do Norte
  • Isabelle Campos de Azevedo Federal University of Rio Grande do Norte
  • Rita de Cássia Lira da Silva Federal University of Rio Grande do Norte
  • Jéssica Valeska Herculano Lima Federal University of Rio Grande do Norte
  • Sandra Lúcia Arantes Federal University of Rio Grande do Norte
  • Allyne Fortes Vitor Federal University of Rio Grande do Norte
  • Viviane Euzébia Pereira Santos Federal University of Rio Grande do Norte
  • Maria Lúcia Ivo Federal University of Mato Grosso do Sul
  • Marcos Antonio Ferreira Júnior Federal University of Rio Grande do Norte
  • Marcos Antonio Ferreira Junior

Abstract

Objective: To analyze the investigations regarding the survival of corneal tissue transplanted into patients affected by keratoconus. Method: This is a review study with the following guiding question: “What are the factors that influence the survival of transplanted corneal tissue in patients with keratoconus?” An integrative review protocol was built for this study to ensure methodological rigor required. The sample selection was through a survey of articles in electronic databases PubMed/MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Scopus and Science Direct in October 2014. Indexed descriptors in MeSH and/or synonyms were used: “keratoconus”; “Corneal transplantation” or “keratoplasty”; “Survival analysis” or “analysis of survival” or “method Kaplan-Meier.” Results: The final sample were thirteen articles available in full in accessible databases. Most of the studies were presented in the retrospective cohort design and used the Kaplan-Meier method for survival analysis. This data varied according to the surgical technique used and the factors that interfere in episodes of rejection postoperatively. Conclusion: The survival of corneal tissue was directly related to the main factors involved in post-transplantation, like rejection, vascular changes, adopted surgical technique and inflammatory processes.

Published
Jun 28, 2016
How to Cite
CRUZ, Giovanna Karinny Pereira et al. Studies on Survival of Corneal Tissue Transplantation in Patients with Keratoconus. International Archives of Medicine, [S.l.], v. 9, june 2016. ISSN 1755-7682. Available at: <http://imed.pub/ojs/index.php/iam/article/view/1623>. Date accessed: 20 nov. 2017. doi: http://dx.doi.org/10.3823/1988.
Section
Ophtalmology

Keywords

Corneal transplantation; Survival analysis; Kaplan-Meier method; Prospective care; Keratoconus

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