Nurses and the Use of Collagenase in the Treatment of Chronic Wounds

Authors

  • Thalys Maynnard Costa Ferreira Universidade Federal da Paraíba
  • Rossana Santos de Andrade Universidade Federal da Paraíba
  • Patrícia Simplício de Oliveira Universidade Federal da Paraíba
  • Carla Lidiane Jácome de Lima Universidade Federal da Paraíba
  • Josefa Danielma Lopes Ferreira Universidade Federal da Paraíba
  • Marta Miriam Lopes Costa Universidade Federal da Paraíba

DOI:

https://doi.org/10.3823/1998

Keywords:

Nursing, Debridement, Nursing Care.

Abstract

Objective: The objective was to verify the skill of nurses about the use of collagenase in the treatment of chronic wounds.

 

Method: A descriptive study of a qualitative approach performed with medical clinic nurses from two hospitals. The data were collected processed using the content analysis technique.

Results: Worked categories: 1. Knowledge about the mechanism of action of collagenase in the treatment of chronic wounds; 2. Reasons for use and destruction of collagenase in the treatment of chronic wounds.

 

Conclusion: The study showed that nurses have knowledge that collagenase is a debriding enzyme that aids in the healing process, particularly by removing the necrotic tissue in wounds; however, there is still the need to improve the relevant knowledge concerning the use of this substance in dressings made in their chronic lesions, even in view of the apparent lack of knowledge about the relevant enzyme peculiarities, such as its mechanism of action.

 

Descriptors: Nursing; Debridement; Nursing Care.

 

Author Biographies

Thalys Maynnard Costa Ferreira, Universidade Federal da Paraíba

Graduate Student of Nursing, Member of the Group of Studies and Research in the Treatment of Wounds-GEPEFE, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

Rossana Santos de Andrade, Universidade Federal da Paraíba

Graduate Student of Nursing, Member of the Group of Studies and Research in the Treatment of Wounds-GEPEFE, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

Patrícia Simplício de Oliveira, Universidade Federal da Paraíba

Nurse, Master of Nursing at the Graduate Program of Nursing-PPGENF/UFPB, Member of the Group of Studies and Research in the Treatment of Wounds-GEPEFE, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

Carla Lidiane Jácome de Lima, Universidade Federal da Paraíba

Nurse, Master of Nursing at the Graduate Program of Nursing-PPGENF/UFPB, Member of the Group of Studies and Research in the Treatment of Wounds-GEPEFE, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

Josefa Danielma Lopes Ferreira, Universidade Federal da Paraíba

Nurse, Master of Nursing at the Graduate Program of Nursing-PPGENF/UFPB, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

Marta Miriam Lopes Costa, Universidade Federal da Paraíba

Nurse, Doctor of Nursing, Department of Nursing-DENC/UFPB, Member of the Group of Studies and Research in the Treatment of Wounds-GEPEFE, Federal University of Paraíba, João Pessoa, Paraíba, Brazil.

References

Leite AP, Oliveira BGRB, Futuro DO, Castilho SR. Effectiveness of using the gel of papain in the wound healing: clinical trial. Online braz j nurs [Internet]. 2011 Oct [Cited 2015 Mar. 16];10(2):2p. Available from: http://www.objnursing.uff.br/index.php/nursing/article/viewFile/3351/pdf

Silva PN, Almeida OAE, Rocha IC. Topical therapy in the treatment of chronic wounds. Enferm glob [Internet]. 2014 Jan [Cited 2015 June 20];33: 46-58. Available from: http://revistas.um.es/eglobal/article/view/165461/156731

Onesti MG, Fino P, Ponzo I, Ruggieri M, Scuderi N. Non-surgical treatment of deep wounds triggered by harmful physical and chemical agents: a successful combined use of collagenase and hyaluronic acid. Int Wound J [Internet]. 2014 [Cited 2015 June 23]. Available from: http://onlinelibrary.wiley.com/doi/10.1111/iwj.12215/pdf.

Gonçalves MBB, Rabeh SAN, Terçariol CAS. Contribuição da educação à distância para o conhecimento de docentes de enfermagem sobre avaliação de feridas crônicas. Rev latinoam enferm [Internet]. 2015 Jan/Feb [Cited 2015 June 2015];23(1). Available from: www.scielo.br/pdf/rlae/v23n1/pt_0104-1169-rlae-23-01-00122.pdf.

Santos AAR, Medeiros ABA, Soares MJGO, Costa MML. Nursing students’ knowledge of wound evaluation and treatment. Rev enferm UERJ [Internet]. 2010 Oct/Dec [Cited 2015 June 21];18(4):547-52. Available from: http://www.facenf.uerj.br/v18n4/v18n4a08.pdf.

Miller JD, Carter E, Hatch Jr DC, Zhubrak M, Giovanco NA, Armstrong DG. Use of colagenase ointment in conjunction with negative pressure wound therapy in the care of diabetic wounds: a case series of six patients. Diabet foot Ankle [Internet]. 2015 Jan [Cited 2015 June 26];6. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309834/.

Santos ICRV, Oliveira RC, Silva MA. Surgical debridement and the legal responsibilities of nurses. Texto & contexto enferm [Internet]. 2013 Jan/Mar [Cited 2015 June 22]; 22(1): 184-92. Available from: http://www.scielo.br/pdf/tce/v22n1/pt_22.pdf.

Brito KKG, Soares MJGO, Silva MA. Nursing care at preventive actions on pressure ulcers. Rev bras ciênc saúde. [Internet]. 2014 Apr/June [Cited 2015 Apr 21]; 40(12). Disponível em: http://www.ufrgs.br/educatele/cursos/arquivos/cuidado-de-enfermagem-nas-acoes-preventivas-nas-ulceras-de-pressao.

Bruzi LM, Mendes DC. The importance of nursing care in managing complications related to fully-implantable catheters. Rev Esc Enferm USP [Internet]. 2011 [Cited 2014 Nov 12];5(2):522-6. Available from: http://www.scielo.br/pdf/reeusp/v45n2/v45n2a30.pdf

Bardin L. Análise de conteúdo. 4 th ed. São Paulo: Edições 70; 2011. 288 p.

Hoppe IC, Granick MS. Debridement of chronic wounds: a qualitative systematic review of randomized controlled trials. Clin Plast Surg [Internet]. 2012 July [Cited 2014 Aug 28];39(3):221–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22732371.

Beitz JM. Wound debridement: Therapeutic options and care considerations. Crit Care Nurs Clin North Am [Internet]. 2012 June [Cited 2015 May 23];24(2):239–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15924892.

Malagutti W, Kakihara CT. Curativos, estomias e dermatologia: uma abordagem multiprofissional. 2nd ed. São Paulo: Martinari; 2014. 637 p.

McCallon SK, Frilot C. A retrospective study of the effects of clostridial collagenase ointment and negative pressure wound therapy for the treatment of chronic pressure ulcers. Wound [Internet]. 2015 Mar [Cited 2015 June 16]; 24(3): 44-53. Available from: http://www.woundsresearch.com/article/retrospective-study-effects-clostridial-collagenase-ointment-and-negative-pressure-wound.

Rosa TJS, Cintra LKL, Freitas KB, Alcântara PFDL, Spacassassi F, Rosa CDP et al. Pressure ulcer: treatment. Acta Fisiátrica [Internet]. 2013 June [Cited 2015 June 28];20(2):106-11. Available from: http://www.actafisiatrica.org.br/detalhe_artigo.asp?id=506.

Ferreira AM, Rigotti MA, Pena SB, Paula DS, Ramos IB, Sasaki VDM. Knowledge and practice of nursing students about caring for patients with wounds. Esc Anna Nery Rev Enferm [Internet]. 2013 Apr/June [Cited 2014 Sept 24]; 17(2): 211-9. Available from: http://www.scielo.br/pdf/ean/v17n2/v17n2a02.pdf.

Cristália Produtos Químicos Farmaceuticos Ltda [Internet]. Kollagenase com Cloranfenicol (colagenase + cloranfenicol): Modelo de bula para o paciente. [cited 2015 Nov 27]. Available from: http://www.anvisa.gov.br/datavisa/fila_bula/frmVisualizarBula.asp?pNuTransacao=9356292013&pIdAnexo=1855200.

Agência Nacional de Vigilância Sanitária (Brasil). Antimicrobianos: bases teóricas e uso clínico. Antimicrobianos - principais grupos disponíveis para uso clínico. Cloranfenicol. Conceito e classificação. Anvisa [Internet]. 2007 [cited 2015 Nov 27]. Available from:

http://www.anvisa.gov.br/servicosaude/controle/rede_rm/cursos/rm_controle/opas_web/modulo1/cloranfenicol.htm.

Conselho Regional de Enfermagem do Distrito Federal. Parecer Coren-DF n 007/2008. Assunto: Tratamento de feridas. Consulta: “Solicita parecer sobre atuação do Enfermeiro no tratamento de feridas, no que diz respeito à autonomia, prescrição de medicamentos, cobertura e procedimentosâ€. Brasília: Coren-DF; 2008 [cited 2015 Nov 25]. Available from: http://www.coren-df.gov.br/site/parecer-coren-df-nd-0122008/.

Conselho Regional de Enfermagem de São Paulo. Parecer Coren –SP n 002/2015 – CT Processo nº 5334/2014. Ementa: Prescrição de coberturas para tratamento de feridas por Enfermeiro. São Paulo: Coren –SP; 2015 [cited 2015 Nov 24]. Available from: http://portal.coren-sp.gov.br/sites/default/files/Parecer%20002-2015%20Prescri%C3%A7%C3%A3o%20coberturas-1.pdf

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Published

2016-07-05

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Section

Global Health & Health Policy

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