Meta-Analysis of Prevalence of Xerostomia in Diabetes Mellitus

  • Luiza Silveira Lessa Universidade do Extremo Sul Catarinense (UNESC)
  • Patrícia Duarte Simões Pires Universidade do Extremo Sul Catarinense (UNESC)
  • Renan Antônio Ceretta Universidade do Extremo Sul Catarinense (UNESC)
  • Indianara Reynaud Toreti Becker Universidade do Extremo Sul Catarinense (UNESC)
  • Luciane Bisognin Ceretta Universidade do Extremo Sul Catarinense (UNESC)
  • Lisiane Tuon Universidade do Extremo Sul Catarinense (UNESC)
  • Priscyla Waleska Simões Universidade do Extremo Sul Catarinense (UNESC)
  • Fernanda Guglielmi Faustini Sônego Universidade do Extremo Sul Catarinense (UNESC)

Abstract

Background: As with other complications of diabetes mellitus, the occurrence of dry mouth can lead to a poor quality of life. Therefore, this study aimed to identify the prevalence of xerostomia in patients with diabetes mellitus through a systematic review and meta-analysis. Method: Systematic review and meta-analysis. Results: After the screening process, 23 studies were included in the meta-analysis. Overall, the incidence of dry mouth was investigated in 1979 people with diabetes (cases) and 1225 controls. The global prevalence of diabetes in xerostomia was 42.22% (95% CI: 33.97%-50.92%). In the analysis by specific subtype, the overall prevalence was 37.42% (95% CI: 22.33%-55.44%) among individuals with Type 1 diabetes and 46.09% (95% CI: 23.99%-69.85%) among those with type 2 diabetes. The prevalence of xerostomia found in Asia (49.01%; 95% CI: 32.08%-66.16%) was higher than that found in Europe (40.04%; 95% CI: 29.58%-51.50%) and America (38.39%; 95% CI: 23.63%-55.65%). Analysis of the case-control studies showed a statistically significant association between xerostomia and diabetes mellitus (OR=3.15; 95% CI: 2.11-4.70; p<0.001). Conclusion: Through the data collected, we can infer that the prevalence of xerostomia in individuals affected by diabetes mellitus types 1 and 2 was high and independent of geographic location.

Published
Sep 23, 2015
How to Cite
SILVEIRA LESSA, Luiza et al. Meta-Analysis of Prevalence of Xerostomia in Diabetes Mellitus. International Archives of Medicine, [S.l.], v. 8, sep. 2015. ISSN 1755-7682. Available at: <http://imed.pub/ojs/index.php/iam/article/view/1309>. Date accessed: 18 aug. 2018. doi: http://dx.doi.org/10.3823/1823.
Section
Dental Medicine

Keywords

Diabetes Mellitus; Xerostomia; Systematic Review; Meta-analysis.

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