Distribution of bacterial uropathogens and their susceptibility patterns over twelve years (2001-2013) in Palestine

  • Ahmad M. Zaid Medical laboratory sciences

Abstract

Background:

The emergence of new resistant strains of bacteria has become one of the most serious global health themes. The medication of UTI's caused by resistant strains has turned to be an economic burden worldwide. Local community evaluation of susceptibility patterns for uropathogens is of great importance to reduce the misuse of empirical antibiotics. This study presents the incidence and wide spectrum of uropathogens in addition to their antibiotic susceptibility patterns.

 

Methods:

A total of 16,883 urine culture samples were included in this retrospective study. The incidence of recovered uropathogens was estimated in the examined urine samples, as well as the sex and age groups of these patients. Furthermore, the antimicrobial susceptibility  for all  identified bacterial isolates were analyzed.

 

Results:

6.539 out of 16,883 urine culture samples produced significant bacterial growth. They were identified to be E. coli, coagulase negative Staphylococci, Streptococcus spp, S aureus, and Klebsiellaspp, with their frequencies as follow (47%, 19.6%, 18.4%, 4.9%, 2.9%, respectively).

 

Gram positive uropathogens showed good susceptibility towards the local commonly used antibiotics in UTIs; Amoxi/clav, Cefuroxime ,Cephalothin , Sulpha /Trimethoprim, Nitrofurantoin, Ciprofloxacin, Ofloxacin and Norfloxacin (83.9%, 80.1%, 70.1%, 36.6%, 65.1, 57.6%, 51.6%, 47.8%, respectively).

 

Gram negative uropathogens showed good susceptibility towards Ciprofloxacin, Ofloxacin, norfloxacin, Cefuroxim,Nitrofurantoin, Sulpha/Trimethoprim, Nalidixic Acid, and Amoxi/clav, (76.1%, 71.8%, 72.9%, 64%, 67.5%, 48.7%, 57.6%, 42.1%, respectively).

 

Conclusions:

It is highly important to monitor the incidence of common uropathogens and their antimicrobial susceptibility patterns regularly in order to maintain the best effective choices of treatment, this will minimize the UTI complications and therapy costs.

Published
Jan 19, 2014
How to Cite
ZAID, Ahmad M.. Distribution of bacterial uropathogens and their susceptibility patterns over twelve years (2001-2013) in Palestine. The International Arabic Journal of Antimicrobial Agents, [S.l.], v. 3, n. 4, jan. 2014. ISSN 2174-9094. Available at: <http://imed.pub/ojs/index.php/IAJAA/article/view/724>. Date accessed: 07 mar. 2021.
Section
Articles

Keywords

Antimicrobial susceptibility uropathogen