Case Study: Pseudomonas aeruginosa Blood Stream Infection showing Derepressed  AmpC β-lactamase Hyper-producing Mutants

  • Jamal Wadi
  • Muhannad Yacoub
  • Nahil  Halloub
  • Rula Mohammad Rashed

Abstract

Here we describe a middle aged-woman who had septic shock caused by a strain of Pseudomonas aeruginosa carrying derepressed AmpC hyper-producing genes. This was brought into view when the strain located in pipracillin/tazobactam area was exposed on agar plate to imipenem by diffusion causing “D-phenomena”. Clinicians and microbiologists have to be aware of this phenomenon for a better choice of antimicrobials in treating their patients.
Published
Feb 25, 2013
How to Cite
WADI, Jamal et al. Case Study: Pseudomonas aeruginosa Blood Stream Infection showing Derepressed  AmpC β-lactamase Hyper-producing Mutants. The International Arabic Journal of Antimicrobial Agents, [S.l.], v. 2, n. 4, feb. 2013. ISSN 2174-9094. Available at: <http://imed.pub/ojs/index.php/IAJAA/article/view/588>. Date accessed: 26 sep. 2021.
Section
Articles

Keywords

Pseudomonas aeruginosa, Derepressed AmpC β-lactamase, Septic shock, chromosomally mediated, D-phenomena.