Case Study: Pseudomonas aeruginosa Blood Stream Infection showing DerepressedÂ AmpCÂ Î²-lactamase Hyper-producing Mutants
Keywords:Pseudomonas aeruginosa, Derepressed AmpC Î²-lactamase, Septic shock, chromosomally mediated, D-phenomena.
AbstractHere we describe a middle aged-woman who had septic shock caused by a strainÂ of Pseudomonas aeruginosa carrying derepressed AmpC hyper-producing genes.Â This was brought into view when the strain located in pipracillin/tazobactam areaÂ was exposed on agar plate to imipenem by diffusion causing â€œD-phenomenaâ€.Â Clinicians and microbiologists have to be aware of this phenomenon for a betterÂ choice of antimicrobials in treating their patients.
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access and Benefits of Publishing Open Access).
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.
Articles are published Under License of Creative Commons Attribution 3.0 License Â©
Copyright policies & self-archiving
|Author's Pre-print:||author can archive pre-print (ie pre-refereeing)|
|Author's Post-print:||author can archive post-print (ie final draft post-refereeing)|
|Publisher's Version/PDF:||author can archive publisher's version/PDF|