Trends of antimicrobial resistance in Escherichia coli isolates from urine cultures of women in Jordan: A 10-year retrospective study

Authors

  • Mustafa Abdulkarim Alrabayah Assistant professor at The University of Jordan/ Amman.
  • Nisreen Abdel-kareem Nadi Anesthesia and Intensive Care resident at Jordan University Hospital
  • Aiman Mohammad Suleiman Anesthesia and Intensive Care resident at Jordan University Hospital
  • Ala' Mohammad Abbad Anesthesia and Intensive Care resident at Jordan University Hospital
  • Hadil Simon Ghanem Anesthesia and Intensive Care resident at Jordan University Hospital
  • Ahmad Mohammad Obeidat Anesthesia and Intensive Care resident at Jordan University Hospital
  • Maysarah Mahdi Alaqrabawi Anesthesia and Intensive Care resident at Jordan University Hospital
  • Moh'd Adnan Yousef Anesthesia and Intensive Care resident at Jordan University Hospital
  • Taima'a Ahmad Harb Anesthesia and Intensive Care resident at Jordan University Hospital
  • Isam Khair Al-Deen Bsisu Anesthesia and Intensive Care resident at Jordan University Hospital

DOI:

https://doi.org/10.3823/849

Keywords:

Antimicrobial resistance, E.coli resistance, urinary tract infection, women, Jordan

Abstract

Background: Urinary tract infection (UTI) is a common medical condition among women. E.coli is the most common causative organism. Appropriate understanding of the development of antimicrobial resistance over the past helps to establish efficient treatment strategies in the future. The study aims to discover antimicrobial resistance trends exhibited by E.coli strains isolated from women urine cultures over the past 10 years.

Methods: A total of 1874 affected urine samples over the years 2009 to 2018 were collectively reviewed and classified according to the response they showed to 24 different antimicrobial disks in the laboratory. Relations between time and resistance evolutionary profiles were calculated.

Results: Gentamicin (p value =0.039), Augmentin (p value =0.017), Cefoxitin (p value =0.001), Cefixime (p value =0.026) fulfilled satisfactory figures in terms of average resistance, regression of resistance, speed of resistance evolution, steadiness of performance, side effects, spectrum range and cost with high significance.

Conclusion: Drugs that showed satisfactory figures are recommended for future treatment protocols in Jordan.

 

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2020-09-28

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