Antibiotic resistance rates among bacterial isolates from infected patients of intensive care unit over the period (2011-2016) in Bursa, Turkey
The Comparison Of The Antibiotic Resistance Rates
Abstract
Background: The aims of this study were to evaluate the microbiological datas for effective infection control and specific antimicrobial stewardship and to report the epidemiology of ICU-acquired infections and the local antimicrobial resistance of pathogen microorganisms.
Methods: Datas were collected between January 2011-October 2016 retrospectively from the cardiology and cardiovascular surgery patients. The identification and antimicrobial susceptibility analyses in clinical isolates of pathogen microorganisms were determined by the automatic device system.
Results: Klebsiella pneumoniae was detected increasingly resistant to imipenem (IMP) significantly (p=0.048). Acinetobacter baumanii was found increasingly resistant to amikacin (AN), gentamicin (GN), trimethoprim-sulfamethoxazole (SXT) and tetracycline (TE) significantly (p=0.045, p=0.030, p=0.006, p=0.027). There was a significantly decrease in the resistant rates of IMP, piperacillin-tazobactam (TPZ), meropenem (MEM) and ciprofloxacin (CIP) for Pseudomonas spp. (p=0.048). In all of the gram-negative microorganisms, significantly increasing resistance rates to cefepime (CEP) was detected (p=0.015). In all of the gram-positive microorganisms, significantly decreasing resistance rates to teicoplanin (TEC) was also detected (p=0.034).
Conclusion: As a result, the inadequacy of infection control measures such as hand hygiene and patient isolation to prevent transmission between patients has increased the carbapenem-resistant Klebsiella pnemoniae (CR-KP) ratio, which is frequently found in recent years in our hospital. However, preferring preemptive treatment as a result of cooperation with microbiology laboratory instead of empirical treatment with antibiotics such as carbapenem and vancomycin caused the decrease in the resistance rates of resistant microorganism.
This work is licensed under a Creative Commons Attribution 4.0 International License.
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access and Benefits of Publishing Open Access).
This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge.
Articles are published Under License of Creative Commons Attribution 3.0 License ©
Copyright policies & self-archiving
This is our Copyright Policy. We are a RoMEO green journal.
| Author's Pre-print: |  author can archive pre-print (ie pre-refereeing) |
| Author's Post-print: | author can archive post-print (ie final draft post-refereeing) |
| Publisher's Version/PDF: | author can archive publisher's version/PDF |
